منابع مشابه
Buccal absorption of ergotamine.
The rate of disappearance of ergotamine from the mouth after buccal administration has been studied in seven subjects. Allowance has been made for non-absorptive losses of the drug due to experimental technique. The absorption of ergotamine across the buccal mucosa appears to be a passive process, pH-dependent but independent of ergotamine concentration or the simultaneous presence of caffeine....
متن کاملAbsorption and bioavailability of nebulized morphine.
During anaesthesia seven patients received a bolus of morphine 10 mg injected into the nebulization reservoir placed between the tracheal tube and the anaesthetic circle (IH). Five days after operation the same seven patients received morphine 10 mg i.m. On both occasions, venous blood samples were taken before and every 15 min after administration over 4.5 h for measurement of free morphine im...
متن کاملAbsorption of vitamin C from the human buccal cavity.
1. Ascorbic acid was absorbed across the mucosa of the human mouth. 2. Omission of sodium ions from the medium decreased the absorption of ascorbic acid. 3. The presence of D-glucose, or 3-O-methyl-D-glucose, increased the absorption of ascorbic acid but D-fructose had little effect and D-mannitol had no effect. 4. Calcium ions also increased ascorbic acid absorption probably by a secondary ef...
متن کاملAbsorption of amino acids from the human buccal cavity.
appropriate controls the concentration of each amino acid could be established. The absence of glycylproline ( < 0 . 5 m ~ ) from the samples were established by t.1.c. From each of two to six animals a minimum of four sacs were prepared from the ileum. Examination of sacs after incubation by lightmicroscopy failed to show any disruption caused by the experimental procedure. Fig. ] ( a ) shows ...
متن کاملAbsorption rates of alphaprodine from the buccal and intravenous routes
Alphaprodine is a rapidly acting synthetic narcotic. The effectiveness and rate of absorption when this drug is administered buccally is not known. The purpose of this study is to investigate absorption rates of alphaprodine administered buccally, (submucosally} and intravenously. Eight healthy male volunteers ranging in age from 19 to 41 years were included Each subject received 0.4 mg/kg of b...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Anaesthesia
سال: 1989
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1989.tb11299.x